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Drug: Magnesium

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Total 11056 results found since Jan 2013.

Aluminum phosphide (celphos) poisoning in children: A 5-year experience in a tertiary care hospital from northern India
Conclusion: The present study highlights that survival among children with ALP poisoning is predicted by dose of ALP ingestion, time lag to medical attention, and higher PRISM score at admission. Use of magnesium sulfate could be associated with better survival among them.
Source: Indian Journal of Critical Care Medicine - January 18, 2014 Category: Intensive Care Authors: Anupama SharmaDishantVikas GuptaJaya Shankar KaushikKundan Mittal Source Type: research

Does magnesium matter in patients of Medical Intensive Care Unit: A study in rural Central India
Conclusion: Hypomagnesemia is associated with a higher mortality rate in critically ill patients. The need for ventilatory support, but not its duration is significantly higher in hypomagnesemic patients. Hypomagnesemia is commonly associated with sepsis and diabetes mellitus. The duration of MICU stay is significantly higher in patients with low serum Mg.
Source: Indian Journal of Critical Care Medicine - July 8, 2015 Category: Intensive Care Authors: Sunil KumarAkshay HonmodeShraddha JainVijay Bhagat Source Type: research

Hypomagnesemia in the intensive care unit: Choosing your gastrointestinal prophylaxis, a case report and review of the literature
We report a case of symptomatic hypomagnesaemia in medical intensive care unit that is strongly related to proton pump inhibitors (PPIs) and provide literature review. A 65-year-old male with severe gastroesophageal reflux on omeprazole 20 mg orally twice a day, who presented to the hospital with abdominal pain, nausea, diarrhea, and new onset seizures. On admission, his serum magnesium level was undetectable. Electrocardiogram showed a new right bundle branch block with a prolonged QT interval. The hypomagnesemia was corrected with aggressive magnesium supplementation and hypomagnesemia resolved only after the PPI was sto...
Source: Indian Journal of Critical Care Medicine - July 5, 2014 Category: Intensive Care Authors: Aileen K WangShweta SharmaPaul KimKaren Mrejen-Shakin Source Type: research

Calcium homeostasis disorder during and after neonatal extracorporeal membrane oxygenation
Conclusions: We confirmed the existence of severe disturbances of calcium homeostasis in neonates on ECMO and supposed the possible damage of calcium regulation. We did not succeed in finding clear explanations of these disturbances.
Source: Indian Journal of Critical Care Medicine - September 8, 2015 Category: Intensive Care Authors: Jerome RambaudIsabelle GuellecJulia GuilbertPierre-Louis LégerSylvain Renolleau Source Type: research

Asthma Care Protocol Implementation in the Pediatric Intensive Care Unit
Asthma is a complex chronic disease characterized by inflammatory disorder causing airflow obstruction due to inflammation, bronchospasms, and mucus plugging. Children who fail to respond to initial first-line therapies often require hospitalization, and many with severe exacerbations and near-fatal asthma require admission to the pediatric intensive care unit (PICU). Nursing care of these PICU patients requires close monitoring and excellent assessment of their respiratory status. Administration of medications, such as albuterol, methylprednisolone, magnesium sulfate, and sedatives, is needed. Close communication with the...
Source: Critical Care Nursing Clinics of North America - June 17, 2023 Category: Nursing Authors: Exie Meredith, Jenilea Thomas Source Type: research

Oxidative stress determined through the levels of antioxidant enzymes and the effect of N-acetylcysteine in aluminum phosphide poisoning
Conclusions: This study suggests that the baseline level of catalase and SOD have reduced in ALP poisoning, but baseline GR level has not suppressed but is rather increasing with due time, and more so in the treatment group. NAC along with supportive treatment may have improved survival in ALP poisoning.
Source: Indian Journal of Critical Care Medicine - October 3, 2014 Category: Intensive Care Authors: Avinash AgarwalRoto RoboNirdesh JainManish GutchShuchi ConsilSukriti Kumar Source Type: research

Aluminum phosphide poisoning: Possible role of supportive measures in the absence of specific antidote
Vijay Kumar Agrawal, Abhishek Bansal, Ranjeet Kumar Singh, Bhanwar Lal Kumawat, Parul MahajanIndian Journal of Critical Care Medicine 2015 19(2):109-112Aluminum phosphide (ALP) poisoning is one of the major causes of suicidal deaths. Toxicity by ALP is caused by the liberation of phosphine gas, which rapidly causes cell hypoxia due to inhibition of oxidative phosphorylation, leading to circulatory failure. Treatment of ALP toxicity is mainly supportive as there is no specific antidote. We recently managed 7 cases of ALP poisoning with severe hemodynamic effects. Patients were treated with supportive measures including gast...
Source: Indian Journal of Critical Care Medicine - February 6, 2015 Category: Intensive Care Authors: Vijay Kumar AgrawalAbhishek BansalRanjeet Kumar SinghBhanwar Lal KumawatParul Mahajan Source Type: research

Successful management of aluminium phosphide poisoning using intravenous lipid emulsion: Report of two cases
We present here two cases of ALP poisoning who were successfully managed by treatment with lipid emulsion and intravenous magnesium sulfate.
Source: Indian Journal of Critical Care Medicine - December 9, 2015 Category: Intensive Care Authors: Udismita BaruahAmeeta SahniHarish C Sachdeva Source Type: research

Anesthesia for children with long QT syndrome: Challenges and solutions from pediatric studies
Conclusion LQTS worth emphasis as the prevalence and associated complications exceed some commonly discussed genetic disorders in anesthesia. Preoperative evaluation of pediatric patients directed to identifying perioperative risk factors and preparation for respective management minimizes potentially fatal complications associated with long QT syndrome.
Source: Trends in Anaesthesia and Critical Care - May 11, 2017 Category: Anesthesiology Source Type: research

High-Dose Magnesium Sulfate Infusion for Severe Asthma in the Emergency Department: Efficacy Study*
Objective: To assess the efficacy of a high-dose prolonged magnesium sulfate infusion in patients with severe, noninfectious–mediated asthma. Design: Prospective, randomized, open-label study. Setting: Twenty-nine–bed pediatric emergency department located in a children’s hospital in Asuncion, Paraguay. Patients: All patients of 6–16 years old who failed to improve after 2 hours of standard therapy for asthma. Interventions: Subjects were randomized to receive magnesium sulfate, 50 mg/kg over 1 hour (bolus) or high-dose prolonged magnesium sulfate infusion of 50 mg/kg/hr for 4 hours (max, 8.000 mg/4 hr). Patien...
Source: Pediatric Critical Care Medicine - February 1, 2016 Category: Pediatrics Tags: Online Clinical Investigations Source Type: research

Asthma changes at a Pediatric Intensive Care Unit after 10 years: Observational study
Conclusion: We observed slight shift toward older age, considerably increased the rate of PICU admission, increased utilization of Ipratropium bromide, magnesium sulfate, and NIV as important modalities of treatment.
Source: Annals of Thoracic Medicine - October 9, 2015 Category: Respiratory Medicine Authors: Ayman A Al-EyadhyMohamad-Hani TemsahAli A. N. AlhaboobAbdulmalik K AldubayanNasser A AlmousaAbdulrahman M AlsharidahMohammed I AlangariAbdulrahman M Alshaya Source Type: research

Determinants of serum magnesium abnormalities and outcome among admissions to the intensive care unit
Publication date: Available online 12 October 2020Source: Anaesthesia Critical Care & Pain MedicineAuthor(s): Kevin B. Laupland, Alexis Tabah, Nicole Jacobs, Mahesh Ramanan
Source: Anaesthesia, Critical Care and Pain Medicine - October 14, 2020 Category: Anesthesiology Source Type: research

Cerebral Oximetry Assessed by Near-Infrared Spectrometry During Preeclampsia: An Observational Study: Impact of Magnesium Sulfate Administration
Objectives: To determine the regional cerebral oxygen saturation of hemoglobin (rcSO2) in severe preeclamptic parturients exhibiting neurologic symptoms compared with healthy pregnant women (control) and to describe the effects of MgSO4 infusion on rcSO2 and cerebral and systemic hemodynamic variables. Design: Prospective, observational study. Setting: Obstetric critical care unit in a university-affiliated hospital. Patients: Twenty severe preeclamptic parturients presenting with neurologic signs before any administration of MgSO4, and 20 control parturients. Intervention: Infusion of MgSO4 in severe preeclamptic patients...
Source: Critical Care Medicine - October 16, 2014 Category: Emergency Medicine Tags: Clinical Investigations Source Type: research

Unpeeling the Evidence for the Banana Bag: Evidence-Based Recommendations for the Management of Alcohol-Associated Vitamin and Electrolyte Deficiencies in the ICU
Conclusions: Based on the published literature, for patients with a chronic alcohol use disorder admitted to the ICU with symptoms that may mimic or mask Wernicke’s encephalopathy, we suggest abandoning the banana bag and utilizing the following formula for routine supplementation during the first day of admission: 200–500 mg IV thiamine every 8 hours, 64 mg/kg magnesium sulfate (approximately 4–5 g for most adult patients), and 400–1,000 μg IV folate. If alcoholic ketoacidosis is suspected, dextrose-containing fluids are recommended over normal saline.
Source: Critical Care Medicine - July 19, 2016 Category: Emergency Medicine Tags: Review Article Source Type: research

Magnesium and Hemorrhage Volume in Patients With Aneurysmal Subarachnoid Hemorrhage
Objectives: We tested the hypothesis that admission serum magnesium levels are associated with extent of hemorrhage in patients with aneurysmal subarachnoid hemorrhage. Design: Single-center prospective observational study. Setting: Tertiary hospital neurologic ICU. Patients: Patients with aneurysmal subarachnoid hemorrhage. Interventions: Clinically indicated CT scans and serum laboratory studies. Measurements and Main Results: Demographic, clinical, laboratory, and radiographic data were analyzed. Extent of initial hemorrhage was graded semi-quantitatively on admission CT scans using the modified Fisher ...
Source: Critical Care Medicine - December 14, 2019 Category: Emergency Medicine Tags: Neurologic Critical Care Source Type: research